Omeprazole improves insulin sensitising action of glp1

darrenG10

darrenG10

Well-known member
We conclude that combination with omeprazole improves the insulin sensitizing actions of GLP-1 therapy and these effects are partially mediated through the decrease in hepatic steatosis and improvement in antioxidant status in the liver.

Link Combination of omeprazole with GLP-1 agonist therapy improves insulin sensitivity and antioxidant activity in liver in type 1 diabetic mice - Pharmacological Reports

Omeprazole therapy significantly improved blood glucose levels, as evidenced by the improvement in HbA1c levels. These findings are consistent with the findings of prior international studies, which used various combinations of anti-glycaemic agents in conjunction with PPIs and assessed the FBS and HbA1c levels.
 
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