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  1. darrenG10

    Both tamoxifen and raloxifene increase your risk of developing blood clots

    Blood clots Both tamoxifen and raloxifene increase your risk of developing blood clots in a vein in your leg (deep venous thrombosis) or in your lungs (pulmonary embolism). These clots can sometimes cause serious problems, and even death. In the major studies looking at these drugs for breast...
  2. darrenG10

    Letro igf1 study

    n both dosage groups a statistically significant increase in the IGF-I levels was observed during three months of letrozole treatment Serum insulin-like growth factor (IGF)-I and IGF-binding protein-3 levels were measured in two groups of postmenopausal women with advanced breast cancer, who...
  3. darrenG10

    Mike Arnold ment

    by Mike Arnold Trestolone ace, more popularly known as Ment, has developed quite a reputation over the last several years for being an exceedingly potent steroid. Combined with its initial long-term absence from the market, its current limited availability, and a market nearly devoid of high...
  4. darrenG10

    How not to become skinny fat

    How not to become skinny fat If your weight goes up or down, does it determine your physical development? Sure, but do you only care if the scale moves? Or, do you care that when that scale goes down, wherein mostly fat was lost and not muscle? And when the scale goes up, do you want it to be...
  5. darrenG10

    Pufa fats build more lean mass and cause fat loss

    Polyunsaturated fats, also called polyunsaturated fatty acids or PUFA, are good fats. They are a type of fat that is good for your heart health Including PUFA foods like olive and canola oil in your diet can reduce your risk of developing health problems. Your body can't make this type of fat...
  6. darrenG10

    Improving digestion

    Few things that will improve digestion fasted cardio it will help speed up gastric emptying push food through your stomach and improve digestion l glutamine 12g daily helps the gut lining and improving digestion sauerkraut natural full of probiotics good for gut health Apple cider vinegar...
  7. darrenG10

    Omeprazole improves insulin sensitising action of glp1

    We conclude that combination with omeprazole improves the insulin sensitizing actions of GLP-1 therapy and these effects are partially mediated through the decrease in hepatic steatosis and improvement in antioxidant status in the liver. Link Combination of omeprazole with GLP-1 agonist therapy...
  8. darrenG10

    Glp1 agonist and inflammation

    The GLP-1 agonist, liraglutide, ameliorates inflammation through the activation of the PKA/CREB pathway in a rat model of knee osteoarthritis Link https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554939/
  9. darrenG10

    Glp1 more findings

    Our data indicate that GLP‐1 infusion restores the anabolic response to EAA provision in older muscle, which may help explain the increase or maintenance in muscle mass observed in these previous studies. We show that GLP-1 up-regulated IGF-1R expression by a protein kinase A-dependent...
  10. darrenG10

    Mike Arnold on testosterone

    Testosterone is key off-season pre contest (cut-bulk)
  11. darrenG10

    Testosterone on myostatin levels study

    Study testosterone is known to suppress myostatin levels in skeletal muscle (33,34) and inhibition of myostatin promotes muscle growth and reduces sarcopenia (35,36,37), we examined the effects of testosterone supplementation on myostatin levels in the gastrocnemius muscle. Context: Fibroblast...
  12. darrenG10

    Phosphatidylserine For suppressing cortisol

    Phosphatidylserine supplements can block certain negative effects of increased cortisol levels for a long time. By reducing and stabilizing cortisol levels, phosphatidylserine also helps regulate metabolism, strengthen memory, improve mood, and reduce inflammation. 800 mg BC-PS supplementation...
  13. darrenG10

    Ginger Extract - a more potent NGF booster than Lion's Mane

    Came across this interesting guys never used it personally but thought I’d share as seen lions mane posted Lion's Mane mushroom extract is well known for its pro-cognitive benefits, as demonstrated in both mice and humans. In mice it significantly increases NGF levels in the brain, which is...
  14. darrenG10

    muscleOps supplements highly recommend

    Guys if you are looking for top quality products that haven’t went up in price yet like other brands I highly recommend muscleOps taste good and aren’t overpriced like we are seeing as there is plenty old stock still left I know you guys love supps give them a try while it’s cheaper than the...
  15. darrenG10

    Lyle McDonald cliffs why we get fat

    Cliffs At a fundamental level, fat storage occurs when caloric intake exceeds caloric output. Now, I know that a lot of people claim that basic thermodynamics don’t hold for humans. Simply, they are wrong. Invariably, the studies used to support this position are based on a faulty data set...
  16. darrenG10

    Combination Formula of Choline, Inositol and L-Methionine

    Combination Formula of Choline, Inositol and L-Methionine Supports fat metabolism For a healthy liver function Combination of vitamins and amino acids Vegan, Vegetarian, Kosher Lipotropic Factors is a specialised combination formula of Choline, Inositol and L-Methionine. Choline is a...
  17. darrenG10

    Shredded in 6 days article interesting read

    Shredded in 6 Days! Overview There are three main factors we're going to be manipulating here to cause your body to dump water fast: 1) Carbohydrates: Low-carb and high protein diets are notably diuretic (puts your body into a fluid flushing mode). Dropping carb intake alone will cause just...
  18. darrenG10

    Matt Porter on contest prep good read

    When you are in great condition a few weeks before a contest and have done everything in your power to be looking great without any unnecessary manipulations -- you technically should be able to coast into the day of the show. However --- I still hear people using depletion methods along with...
  19. darrenG10

    Online coaching

    Just going too put it here want too expand and begin doing this as I’ve helped others with diet training even ones who’ve been with big named coaches like kuba say they felt looked the best they ever have It’s something I love and take serious it’s my passion and joy is seeing others improve...
  20. darrenG10

    Rip Cedric

    Best tall bb of our generation rip
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